They can’t be at home now.
He can’t know so much.
They can’t be playing in the yard now. It is late.
She can’t be still sleeping. It is already ten o’clock.
He can’t have missed the train.
She can’t have deceived me.
You can’t have made such a mistake.
She can’t have failed the exam.
She can’t have betrayed me.
He can’t have given up smoking (have stopped smoking).
He can’t have done it.
He can’t have become a doctor.
He can’t have translated this book.